มักได้แสดงในบทบาทพระเอกที่มีบุคลิกลักษณะเป็นผู้นำ ฉลาดและมีเสน่ห์ เป็นนักแสดงชายถูกจัดเป็นอันดับที่ 2 ใน AFI's 100 Years Greatest Male Star of All Time โดย American Film Institute
รายชื่อหนัง
This Is the Night (1932) Sinners in the Sun (1932) Singapore Sue (1932) (short subject) Merrily We Go to Hell (1932) Devil and the Deep (1932)
Blonde Venus (1932) Hot Saturday (1932) Madame Butterfly (1932) Hollywood on Parade (1932) (short subject) She Done Him Wrong (1933)
The Woman Accused (1933) Hollywood on Parade No. 9 (1933) (short subject) The Eagle and the Hawk (1933) Gambling Ship (1933) I'm No Angel (1933)
Alice in Wonderland (1933) Thirty Day Princess (1934) Born to Be Bad (1934) Kiss and Make Up (1934) Ladies Should Listen (1934)
Enter Madame (1935) Wings in the Dark (1935) The Last Outpost (1935) Pirate Party on Catalina Isle (1935) (short subject) Sylvia Scarlett (1935)
The Amazing Quest of Ernest Bliss (1936) Big Brown Eyes (1936) Suzy (1936) Wedding Present (1936) When You're in Love (1937)
Topper (1937) The Toast of New York (1937) The Awful Truth (1937) Bringing up Baby (1938) Holiday (1938)
Gunga Din (1939) Only Angels Have Wings (1939) In Name Only (1939) His Girl Friday (1940) My Favorite Wife (1940)
The Howards of Virginia (1940) The Philadelphia Story (1940) Penny Serenade (1941) Suspicion (1941) The Talk of the Town (1942)
Once Upon a Honeymoon (1942) Mr. Lucky (1943) Destination Tokyo (1943) Once Upon a Time (1944) Road to Victory (1944) (short subject)
None But the Lonely Heart (1944) Arsenic and Old Lace (1944) Without Reservations (1946) (Cameo) Night and Day (1946) Notorious (1946)
The Bachelor and the Bobby-Soxer (1947) The Bishop's Wife (1947) Mr. Blandings Builds His Dream House (1948) Every Girl Should Be Married (1948) I Was a Male War Bride (1949)
Crisis (1950) People Will Talk (1951) Room for One More (1952) Monkey Business (1952) Dream Wife (1953)
To Catch a Thief (1955) An Affair to Remember (1957) The Pride and the Passion (1957) Kiss Them for Me (1957) Indiscreet (1958)
Houseboat (1958) North by Northwest (1959) Operation Petticoat (1959) The Grass Is Greener (1960) That Touch of Mink (1962)
Charade (1963) Father Goose (1964) A Tribute to the Will Rogers Memorial Hospital (1965) (short subject)
Walk, Don't Run (1966) Elvis: That's the Way It Is (1970) (documentary) The Nativity (1982) (short subject, introductory narration) George Stevens: A Filmmaker's Journey (1984) (voice only)